1.
Braz. j. med. biol. res
;
20(6): 837-43, 1987. ilus
Article
in English
| LILACS
| ID: lil-77464
ABSTRACT
An inhibitor of glucose 6-phosphatase, isosteviol, was used in liver perfusion experiments to obtain a rough estimate of the control strength of the enzyme. Isosteviol only inhibited glucose release at high concentrations (1 mM), well above that needed for half-maximal action (70 micrnM). The decrease in glucose release was followed by an increase in the intracellular glucose 6-phosphate concentration. It was concluded that the control strength of glucose-6-phosphatase is relatively low
Subject(s)
Rats , Animals , Diterpenes/pharmacology , Liver/metabolism , Glucosephosphates/antagonists & inhibitors , Glucose/metabolism , Glucosephosphates/metabolism , Perfusion , Phosphorylases/metabolism
2.
Arq. biol. tecnol
;
27(4): 419-38, 1984.
Article
in Portuguese
| LILACS
| ID: lil-25095